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Updated December 13th, 2018 at 17:28 IST

Probiotics may help patients suffering from bipolar disorder

Probiotics--often thought of as good bacteria can act as a potential avenue for treatment of bipolar and other psychiatric mood disorders

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Probiotics--often thought of as good bacteria can act as a potential avenue for treatment of bipolar and other psychiatric mood disorders.

Currently, the standard treatment for bipolar disorder, a psychiatric condition characterised by dramatic shifts in mood from depression to mania, includes a combination of psychotherapy and prescription medications such as mood stabilisers and antipsychotics.

However, a new study from Baltimore's Sheppard Pratt Health System found that a probiotic supplement may reduce inflammation of the gut, which is known to exacerbate bipolar disorder.

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Probiotic organisms are non-pathogenic bacteria that, when present in the gut flora, are known to improve the overall health of the host.

The research demonstrated a strong link between the gastrointestinal tract and the central nervous system. This connection, named the 'gut-brain axis' (GBA), allows for crosstalk between the endocrine, immune, and autonomic nervous systems. The GI tract is also home to the intestinal microbiome, a complex population of roughly 100 trillion microorganisms that interact with the mucosal lining of the GI tract.

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Researchers also found mounting evidence, linking imbalances in the microbial species that make up the gut microbiome to a number of health problems including allergies, autoimmune disorders, and psychiatric mood disorders. Overall, the results indicated that changes in intestinal inflammation can alter the trajectory of psychiatric mood disorders

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Published December 13th, 2018 at 17:28 IST

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