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Updated March 29th 2025, 18:33 IST

This Is The Organ Most Affected by Extended Space Travel, Check Details

Structure and function of kidneys are altered by spaceflight, with galactic radiation causing permanent damage that would jeopardize any long-distance mission.

Reported by: Manas Gupta
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Study reveals Kidney is most affected by extended space travel
Study reveals Kidney is most affected by extended space travel | Image: X

Science News: Structure and function of the kidneys are altered by spaceflight, with galactic radiation causing permanent damage that would jeopardize any long-distance mission, a study revealed. 

While several studies have suggested health risks for astronauts since humans first traveled beyond Earth's protective atmosphere, the new findings provide insight into the underlying causes of kidney-related issues.

A study was conducted under a University College London-led initiative involving over 40 institutions on five continents.

The team analyzed data from 20 research cohorts and samples associated with over 40 Low Earth orbit missions to the International Space Station, along with 11 simulations involving mice and rats.

This study is the most extensive analysis of kidney health during spaceflight to date and includes the first health dataset for commercial astronauts.

Additionally, it included seven simulations in which mice were exposed to radiation that simulated up to 2.5 years of cosmic travel beyond Earth’s magnetic field.

Function of Kidney Can Get Altered in Spaceflight

Findings revealed that the structure and function of the kidneys are altered by spaceflight, with galactic radiation causing permanent damage that would jeopardize any long-distance mission.

Dr Keith Siew from the London Tubular Centre at the UCL Department of Renal Medicine and his team have developed a detailed understanding of what happens when living organisms, including humans, experience space-like conditions for extended periods.

The team analyzed data from 20 different research cohorts and over 40 missions to the International Space Station, along with 11 simulations involving mice and rats. 

This research is the largest of its kind, providing the first health dataset for commercial astronauts.

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The study also included seven experiments where mice were exposed to radiation mimicking up to 2.5 years of cosmic travel outside Earth’s magnetic field.

“We know the health issues astronauts face on shorter space missions, such as the increased risk of kidney stones, but we don’t fully understand why these problems occur, nor do we know what will happen during longer trips like a mission to Mars,” Dr Siew said. 

The findings showed that spaceflight alters kidney structure and function, with cosmic radiation causing irreversible damage that could jeopardize long-term missions. 

Published March 29th 2025, 18:33 IST