One of the rivalries that brought John Cena at the forefront was against Triple H. Cena made Triple H tap out at WrestleMania 21.
Source: WWE
John Cena elevated the stature of CM Punk in WWE. The two came across in the ring many a times.
Source: WWE.com
Brock Lesnar the beast met super Cena after WrestleMania 28. The two have fought a number of times and each time Cena has showcased his prowess against Lesnar.
Source: wwe.com
Kurt Angle was the first superstar John Cena had a match against. The clash was the face of the ruthless aggression segment.
Source: Kurt Angle
Randy Orton may go down as the biggest rival of John Cena in WWE.