Updated June 6th, 2024 at 22:26 IST

Heart-Healthy Behaviours Linked To Reduced Cell Ageing, Mortality Risk

The study findings revealed a compelling association between higher scores on Life’s Essential 8 and reduced risk of developing cardiovascular diseases.

Heart health | Image:Freepik
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A recent study published in the Journal of the American Heart Association sheds light on the profound impact of heart-healthy behaviors on longevity. According to the U.S. Centre for Disease Control and Prevention, heart disease remains a leading cause of death across various demographic groups in the United States. However, the study suggests that embracing what the American Heart Association terms "Life’s Essential 8" can mitigate the risk of heart disease and mortality, irrespective of age.

Researchers examined data from 5,682 adults, predominantly women, with an average age of 56. Through interviews, physical examinations, and laboratory tests, participants' adherence to Life’s Essential 8 was evaluated. These behaviors encompassed factors such as sleep patterns, smoking habits, physical activity levels, and dietary choices, alongside clinical measurements like body mass index, blood sugar, cholesterol, and blood pressure.

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Image credit: Unsplash
Image credit: Unsplash

The study findings revealed a compelling association between higher scores on Life’s Essential 8 and reduced risk of developing cardiovascular disease and mortality. Each incremental increase in the Life’s Essential 8 score corresponded with a significant decrease in the likelihood of cardiovascular disease, cardiovascular-related mortality, and overall mortality.

Furthermore, individuals genetically predisposed to accelerated biological aging experienced pronounced benefits from adhering to heart-healthy behaviours. Notably, the study identified DNA methylation, an epigenetic modification influencing gene expression, as a potential mechanism mediating these effects.

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The emphasis was also placed on the role of lifestyle factors such as exercise and balanced nutrition in modulating DNA methylation patterns, thus mitigating cellular aging processes. Exercise, in particular, was highlighted for its ability to induce favorable changes in gene expression, promoting cellular health and longevity.

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Image credit: Unsplash

The study underscores the importance of adopting heart-healthy behaviors in enhancing both longevity and overall well-being. By elucidating the intricate interplay between lifestyle factors and biological aging, it offers valuable insights into preventive strategies against age-related diseases like heart disease.

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Published June 6th, 2024 at 22:26 IST