Even though their mission was extended far beyond the original schedule, Williams and Wilmore made the most of their time. They engaged in more than 900 hours of research and development, conducting over 150 scientific experiments. Some of their key contributions include studying the effects of microgravity on biological systems and testing new technologies for long-duration space travel. One of their significant experiments was testing the European Enhanced Exploration Exercise Device (E4D), which combines cycling, rowing, and resistance exercises to help astronauts maintain their health in space. Their research on muscle and bone loss will be crucial for future deep-space missions.