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Updated 28 June 2024 at 19:42 IST

NiedlFree Technologies: Revolutionizing the Delivery of Biologics and Non-Biologics

In a groundbreaking move that promises to redefine the administration of drugs, NiedlFree Technologies has developed a disruptive technology.

Reported by: Digital Desk
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NiedlFree Technologies: Revolutionizing the Delivery of Biologics and Non-Biologics | Image: hh

New Delhi: In a groundbreaking move that promises to redefine the administration of drugs, NiedlFree Technologies has developed a disruptive technology that transforms traditional injectables into convenient oral and nasal sprays. With their innovative platform, NiedlFree is bringing "COMFORT, CONVENIENCE & COMPLIANCE" to the forefront of medical treatments, eliminating the need for painful injections and frequent hospital visits.

Breaking Scientific Barriers

NiedlFree, as the name suggests, has created a transformational and patented technology that replaces the injectable route for both biologics and non-biologics. This revolutionary platform converts drugs into an easy-to-administer oral liquid or nasal spray, offering a new level of convenience for patients and healthcare providers alike.

Key Elements of Success
The success of NiedlFree's technology lies in their expertise in overcoming solubility issues and the use of functionalized nanoparticles of varying sizes. By selectively utilising ligands or carriers that naturally line the gastrointestinal epithelium, NiedlFree ensures efficient drug delivery.

A unique aspect of NiedlFree’s oral delivery system is the double encapsulation with functionalized inner and outer layers. This innovative encapsulation technique provides stability and resistance to the active ingredient, protecting it from the harsh physical and physiological challenges it faces as it travels from the oral cavity to the intestinal epithelial surface.

Unmatched Bio-Availability

NiedlFree’s technology has demonstrated high drug absorption rates, resulting in an excellent pharmacokinetic (PK) profile with bio-availability unmatched by any other company in the world. The materials used in their formulations are classified under the Generally Recognized As Safe (GRAS) category, ensuring a high safety profile.

Transforming Medical Treatments

NiedlFree is currently focusing on transforming injectables into oral or nasal delivery systems for several critical medical conditions, including:
Diabetes: Developing oral formulations of insulin and its analogues.

Osteoporosis: Converting teriparatide injections into a more convenient oral form.

Cancer and Auto-Immune Conditions: Innovating oral delivery systems for monoclonal antibody (mAb) drugs used in the treatment of cancers and autoimmune diseases like rheumatoid arthritis.

Diabetes and Obesity: Creating oral formulations of liraglutide, a GLP-1 peptide.

Cognitive Disorders: Developing a novel nasal spray formulation for treating cognitive disorders such as memory loss, Alzheimer’s, and Parkinson’s disease.

An Indian Innovation with Global Impact

NiedlFree Technologies is an Indian innovation poised to transform global healthcare. By breaking down the barriers of traditional drug delivery methods, NiedlFree is paving the way for a new era in medical treatment, where comfort, convenience, and compliance are paramount. This groundbreaking technology not only improves patient experience but also enhances treatment outcomes, making it a true game-changer in the healthcare industry.

As NiedlFree continues to develop and refine its technology, the future of drug administration looks brighter and more patient-friendly than ever before. The days of painful injections and frequent hospital admissions may soon be a thing of the past, thanks to the pioneering efforts of NiedlFree Technologies.

Published 28 June 2024 at 19:42 IST